Lab Grown Blood Transfusion : First Trial and its Benefits

Did you hear blood grown in a laboratory? 

Yes, that’s true, the miracle of lab-grown blood happened. The milestone of lab-grown blood was achieved in the US, where the world’s first lab grown blood transfusion was carried out by a team at Stanford University. The researchers hope their work could eventually lead to a treatment for people with rare blood types, who often struggle to find blood donations from matching donors. The treatment is also seen as a potential way to increase the blood supply and reduce the risk of transmission of diseases such as HIV and hepatitis C.

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In the clinical trial, which was funded by the US National Institutes of Health, two patients with a rare blood type were transfused with red blood cells grown in a laboratory. The patients did not experience any adverse effects and their bodies appeared to tolerate the transfusions well.

 

Who did this & which technology was used in lab-grown blood transfusion?

Dr. Stephen R. Quake, the senior author of the study, said in a statement about lab grown blood transfusion: “This is proof of principle that we can generate red blood cells outside of the body and transfuse them into humans. “This is the first time cells have been made outside the body and used to treat patients, and we showed that it is safe.” The researchers used a technique to lab-grown blood known as “directed differentiation” to grow the red blood cells from stem cells.

 

Where did lab grown blood wonderful miracle happen?

The trial took place at the University of California, San Francisco (UCSF), and included 10 patients with thalassemia, a blood disorder that affects hemoglobin production. The patients were given transfusions of red blood cells that had been grown in a lab from stem cells. The trial was considered a success, as all 10 patients showed an improvement in their condition after receiving the transfusions. This is a significant development, as it opens up the possibility of using lab-grown blood to treat other conditions that require transfusions, such as sickle cell disease and anemia.

This is the first time that lab grown blood transfused has been into humans, but it is not the first time that artificially-produced blood has been used in transfusions. In 2018, the first clinical trial of lab grown blood transfusions using blood that had been produced using synthetic biology was conducted at Stanford University. In that trial, two patients with beta-thalassemia were given transfusions of red blood cells that had been produced in a lab using yeast.

The trial is being run by the National Health Service (NHS) Blood and Transplant Department, which is responsible for collecting and distributing blood and organ donations in England. The process of creating artificial blood involves taking stem cells from the bone marrow of adult donors and growing them into mature red blood cells. The cells are then purified and stored in liquid nitrogen, to be used when needed. In a statement, Dr. David Roberts, head of research and development at NHS Blood and Transplant, said that while the first two patients had been given just a small amount of the artificial blood, the hope was that it could eventually be used to treat larger volumes of blood. “We have taken the first steps in what could be a major medical advance for patients. If this technology can be developed into a safe and reliable way to generate blood on demand, it could make a huge difference for patients,” he said. The first patient to receive the artificial blood, a 23-year-old woman, was given just a small amount of the cells, to check that the treatment was safe. The second patient, a 27-year-old woman, was given a slightly larger dose, to see how the cells behaved in her body. Both patients were said to have tolerated the treatment well, with no serious side effects. The NHS said that the trial was still in the very early stages and it would be some time before it was known if artificial blood could be used as a long-term treatment for patients. The NHS Blood and Transplant Department has been working on artificial blood for several years. In 2015, it was granted $5 million in funding from the British government to bring the treatment to clinical trials.

How does lab grown blood help people? 

U.K. researchers say the technology could significantly improve treatment for people with blood disorders and rare blood types. “This is a significant step forward,” said study co-author Paolo de Fabritiis, a professor at the University of Edinburgh’s School of Biological Sciences. “We have been able to produce large quantities of blood with a method that could be scaled up for industrial production.” The blood cells were created by reprogramming adult skin cells to become stem cells and then coaxing them to become blood cells. Researchers have used a similar technique to create other cell types, including nerve cells, heart cells, and pancreatic cells. The researchers said the blood cells they created could be used in transfusions and to study how blood cells develop and what happens when they become diseased. The study appears in the journal Nature.

 

How does the lab grown blood technology work?

The Blood grown technology works by taking a sample of blood from the patient and then separating the blood cells from the plasma. The plasma is then mixed with a special solution that contains nutrients and growth factors. The mixture is then placed in a bioreactor where it is incubated for a period of time. The bioreactor provides the ideal environment for the blood cells to grow and multiply. Once the cells have multiplied, they are then injected back into the patient’s body.

 

How much will lab-grown blood cost?

There is no definitive answer to this question as the price of Blood grown will vary depending on a number of factors, including the supplier and the specific needs of the customer. However, it is generally agreed that Blood grown will cost more than traditional methods of blood production. This is difficult to predict as lab-grown blood transfusion technology is still in development. However, it is estimated that lab-grown blood transfusion will be significantly cheaper than blood from donors.

You can also read this: BLOOD TRANSFUSION

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